Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 19/20 | 0.55 |
| ▸ | PLG | P00747 | 10/20 | 0.55 |
| ▸ | PLAT | P00750 | 6/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6433166 | 0.86 | PLAU (0.73) | PLAUPLGPLATMMP1MMP13 | |
| Hydrochloric Acid SCHEMBL6432644 | 0.86 | PLAU (0.71) | PLAUPLGPLATMMP1MMP13 | |
| SCHEMBL6433118 | 0.84 | PLAU (0.59) | PLAUPLGPLATMMP1MMP13 | |
| SCHEMBL6437186 | 0.80 | PLAU (0.71) | PLAUPLGPLAT | |
| SCHEMBL6432884 | 0.80 | PLAU (0.71) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL6436711 | 0.79 | PLAU (0.70) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL6432895 | 0.79 | PLAU (0.70) | PLAUPLGPLAT | |
| SCHEMBL7085779 | 0.79 | PLAU (0.72) | PLAUPLGPLAT | |
| SCHEMBL6439525 | 0.79 | PLAU (0.76) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL6436566 | 0.78 | PLAU (0.70) | PLAUPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077945-B1 | ISOQUINOLINES AS UROKINASE INHIBITORS | PFIZER (US) | 2003-01-08 | — | — | EP | claimed |