Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Nitrogen. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrogen SCHEMBL6395401 | 0.82 | — | — | |
| Nitrogen SCHEMBL38 | 0.82 | — | — | |
| Nitrogen SCHEMBL9614346 | 0.82 | — | — | |
| Bromide SCHEMBL726284 | 0.82 | — | — | |
| Nitrogen SCHEMBL175740 | 0.82 | — | — | |
| Bromide SCHEMBL3162882 | 0.82 | — | — | |
| Nitrogen SCHEMBL1251397 | 0.67 | — | — | |
| Bromide SCHEMBL3673188 | 0.67 | — | — | |
| Nitrogen SCHEMBL3261354 | 0.67 | — | — | |
| Nitrogen SCHEMBL253623 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947634-A | Preparation method of 2, 5-dibromo methyl benzoate | 清源创新实验室 | 2023-10-27 | — | — | CN | claimed |
| CN-116891399-A | Preparation method of 2, 5-dibromo-1, 3-dichlorobenzene | 清源创新实验室 | 2023-10-17 | — | — | CN | claimed |
| US-3947512-A | FROM AROMATIC DIAZONIUM COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-03-30 | — | — | US | claimed |
| CN-116947634-A | Preparation method of 2, 5-dibromo methyl benzoate | 清源创新实验室 | 2023-10-27 | — | — | CN | disclosed |
| CN-116891399-A | Preparation method of 2, 5-dibromo-1, 3-dichlorobenzene | 清源创新实验室 | 2023-10-17 | — | — | CN | disclosed |
| US-8883780-B2 | Crystal of a benzoxazinone compound | NORGINE B.V. (NL) | 2014-11-11 | — | — | US | disclosed |
| US-20120101090-A1 | CRYSTAL OF A BENZOXAZINONE COMPOUND | NORGINE B. V. (NL) | 2012-04-26 | — | — | US | disclosed |
| EP-2423203-A1 | CRYSTAL OF BENZOXAZINONE COMPOUND | Norgine BV (NL) | 2012-02-29 | — | — | EP | disclosed |
| US-7875753-B2 | formed by reacting aryldiazonium bromide with vinylidene chloride in presence of copper salt and bromide source | BAYER CROPSCIENCE AG (DE) | 2011-01-25 | — | — | US | disclosed |
| WO-2010105739-A1 | AROMATIC 2-BROMO-2,2-DICHLOROETHYL COMPOUNDS AND METHODS FOR THE PRODUCTION THEREOF | BAYER CROPSCIENCE AG (DE) | 2010-09-23 | — | — | WO | disclosed |
| US-20100234651-A1 | 2-Bromo-2,2-Dichloroethyl Aromatics and Process for Preparation Thereof | BAYER CROPSCIENCE AG (DE) | 2010-09-16 | — | — | US | disclosed |
| US-20040073030-A1 | Process for the preparation of quinolone derivatives | NATCO PHARMA LIMITED (IN) | 2004-04-15 | — | — | US | disclosed |
| US-20040068139-A1 | Aromatic carboxylic acids, acid halides thereof and processes for preparing both | SUMITOMO BAKELITE COMPANY, LTD. (JP) | 2004-04-08 | — | — | US | disclosed |
| EP-1346975-A1 | AROMATIC CARBOXYLIC ACIDS, ACID HALIDES THEREOF AND PROCESSES FOR PREPARING BOTH | SUMITOMO BAKELITE CO., LTD. (JP) | 2003-09-24 | — | — | EP | disclosed |
| EP-1282603-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF QUINOLONE DERIVATIVES | Natco Pharma Limited (IN) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001085692-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF QUINOLONE DERIVATIVES | NATCO PHARMA LIMITED (IN) | 2001-11-15 | — | — | WO | disclosed |
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3970454-A | N,N-DIALKYL-1,2,3,4-TETRAHYDRO-5-AMINO-8-HYDROXY-QUINOLINIUM | EASTMAN KODAK COMPANY (US) | 1976-07-20 | — | — | US | disclosed |
| US-3947512-A | FROM AROMATIC DIAZONIUM COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-03-30 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |