Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8233490 | 0.86 | TAAR1 (0.46) | TAAR1PNMTLMNAHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL4493567 | 0.84 | TAAR1 (0.45) | TAAR1PNMTNPSR1LMNAHTR2C | |
| SCHEMBL18494712 | 0.83 | TAAR1 (0.40) | TAAR1GAABACE1SMN1; SMN2MAPT | |
| SCHEMBL30728872 | 0.79 | TAAR1 (0.42) | TAAR1GAABACE1SMN1; SMN2MAPT | |
| SCHEMBL17972850 | 0.79 | TAAR1 (0.42) | TAAR1GAABACE1SMN1; SMN2MAPT | |
| SCHEMBL802985 | 0.78 | GAA (0.41) | TAAR1GAABACE1SMN1; SMN2MAPT | |
| SCHEMBL21631949 | 0.77 | PTGFR (0.43) | TAAR1GAASMN1; SMN2MAPTRAB9A | |
| SCHEMBL21718832 | 0.75 | TAAR1 (0.38) | TAAR1GAABACE1SMN1; SMN2MAPT | |
| SCHEMBL8489151 | 0.75 | GAA (0.40) | TAAR1GAABACE1SMN1; SMN2MAPT | |
| SCHEMBL21656361 | 0.73 | SMN1; SMN2 (0.38) | TAAR1GAASMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |
| US-5658907-A | THIOUREA VIRICIDES | MEDIVIR A/B (SE) | 1997-08-19 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | disclosed |