Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 7/20 | 0.48 |
| ▸ | CDK8 | P49336 | 7/20 | 0.48 |
| ▸ | CDK19 | Q9BWU1 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.32 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700630 | 0.77 | CCNC (0.47) | CCNCCDK8CDK19GAACDK9 | |
| SCHEMBL6976237 | 0.76 | CCNC (0.55) | CCNCCDK8CDK19KDM4EGAA | |
| SCHEMBL6978882 | 0.76 | CCNC (0.55) | CCNCCDK8CDK19GAACDK9 | |
| SCHEMBL6975855 | 0.74 | CCNC (0.45) | CCNCCDK8CDK19ALDH1A1CDK9 | |
| SCHEMBL6974246 | 0.74 | CCNC (0.45) | CCNCCDK8CDK19ALDH1A1CDK9 | |
| SCHEMBL6967359 | 0.74 | CCNC (0.56) | CCNCCDK8CDK19KDM4EPOLB | |
| SCHEMBL6977569 | 0.74 | CCNC (0.53) | CCNCCDK8CDK19ALDH1A1GAA | |
| SCHEMBL6968247 | 0.74 | GAA (0.43) | CCNCCDK8CDK19KDM4EPOLB | |
| SCHEMBL6980131 | 0.74 | CCNC (0.55) | CCNCCDK8CDK19KDM4EPOLB | |
| SCHEMBL6975301 | 0.70 | CCNC (0.51) | CCNCCDK8CDK19KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120415-B1 | SUBSTITUTED ISOXAZOLYLTHIOPHENE COMPOUNDS | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-6355663-B1 | AN ENHANCING AGENT FOR THE ACTION OF CELL DIFFERENTIATION INDUCTION FACTORS FOR BONE DISORDERS AND NERVOUS SYSTEM DISORDERS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-12 | — | — | US | disclosed |
| EP-1120415-A1 | SUBSTITUTED ISOXAZOLYLTHIOPHENE COMPOUNDS | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2001-08-01 | — | — | EP | disclosed |