Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 13/20 | 0.41 |
| ▸ | PPARD | Q03181 | 6/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727296 | 0.91 | PPARG (0.47) | PPARGFFAR1KDRPPARAPPARD | |
| SCHEMBL4727180 | 0.88 | PPARG (0.57) | PPARGFFAR1KDRPPARA | |
| SCHEMBL6971740 | 0.86 | FFAR1 (0.54) | PPARGFFAR1KDRPPARA | |
| SCHEMBL8341311 | 0.85 | PPARG (0.42) | PPARGFFAR1KDRPPARAPPARD | |
| SCHEMBL5080602 | 0.84 | FFAR1 (0.61) | PPARGFFAR1KDRPPARAPPARD | |
| SCHEMBL6973891 | 0.84 | KDR (0.60) | PPARGFFAR1KDRPPARA | |
| SCHEMBL6969705 | 0.83 | FFAR1 (0.45) | PPARGFFAR1KDRPPARAPPARD | |
| SCHEMBL6052222 | 0.82 | PPARG (0.50) | PPARGFFAR1PPARA | |
| SCHEMBL8801421 | 0.82 | PPARG (0.50) | PPARGPPARAPPARD | |
| SCHEMBL6966826 | 0.81 | PPARG (0.50) | PPARGFFAR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783496-B9 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| EP-0783496-B1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-26 | — | — | EP | disclosed |
| US-5965589-A | AN ACTIVE MATERIAL HAVING HYPOGLYCEMIC ACTIVITY AND BLOOD LIPID LOWERING ACTIVITY, FOR USE AS AN ANTIDIABETIC AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-12 | — | — | US | disclosed |