Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.48 |
| ▸ | PPARA | Q07869 | 15/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960068 | 0.90 | PPARG (0.56) | PPARGPPARA | |
| SCHEMBL5080606 | 0.89 | FFAR1 (0.59) | PPARGPPARAFFAR1 | |
| SCHEMBL8341159 | 0.85 | FFAR1 (0.52) | PPARGPPARAFFAR1 | |
| SCHEMBL6052232 | 0.85 | PPARG (0.47) | PPARGPPARAFFAR1 | |
| SCHEMBL6960218 | 0.84 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL6973894 | 0.83 | KDR (0.58) | PPARGPPARAFFAR1 | |
| SCHEMBL7487426 | 0.83 | PPARG (0.48) | PPARGPPARAFFAR1 | |
| SCHEMBL6968339 | 0.83 | FFAR1 (0.61) | PPARGPPARAFFAR1 | |
| SCHEMBL5083107 | 0.83 | PPARG (0.43) | PPARGPPARAFFAR1 | |
| SCHEMBL4727181 | 0.83 | PPARG (0.54) | PPARGPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783496-B9 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| EP-0783496-B1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-26 | — | — | EP | disclosed |
| US-5965589-A | AN ACTIVE MATERIAL HAVING HYPOGLYCEMIC ACTIVITY AND BLOOD LIPID LOWERING ACTIVITY, FOR USE AS AN ANTIDIABETIC AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-12 | — | — | US | disclosed |