Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1536321 | 0.85 | CHRNA4 (0.52) | KDM4EALDH1A1CHRNA4SMPD1MAPT | |
| SCHEMBL7896956 | 0.79 | SMPD1 (0.50) | ALDH1A1CHRNA4SMPD1MAPTTP53 | |
| SCHEMBL9963198 | 0.79 | CHRNA4 (0.39) | KDM4EALDH1A1CHRNA4SMPD1MAPT | |
| SCHEMBL23930577 | 0.78 | CHRNA4 (0.38) | KDM4EALDH1A1CHRNA4SMPD1MAPT | |
| SCHEMBL7311748 | 0.78 | SMPD1 (0.46) | KDM4EALDH1A1CHRNA4SMPD1MAPT | |
| SCHEMBL7048303 | 0.78 | MAPT (0.41) | KDM4EALDH1A1MAPTATAD2CA12 | |
| SCHEMBL23930634 | 0.78 | SMPD1 (0.43) | KDM4ECHRNA4SMPD1MAPTLMNA | |
| SCHEMBL7055336 | 0.77 | MAPT (0.43) | KDM4EALDH1A1MAPTCA12CA1 | |
| SCHEMBL4758485 | 0.77 | SMPD1 (0.45) | KDM4EALDH1A1CHRNA4SMPD1LMNA | |
| SCHEMBL5888236 | 0.77 | SMPD1 (0.58) | ALDH1A1CHRNA4SMPD1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |