Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27553866 | 0.85 | KDM4E (0.32) | KDM4E | |
| SCHEMBL6934565 | 0.84 | KDM4E (0.35) | KDM4EMAPTGALR3HTTSMN1; SMN2 | |
| SCHEMBL5228462 | 0.82 | KDM4E (0.34) | KDM4EMAPTGALR3HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7110990 | 0.78 | GAA (0.33) | KDM4EGAA | |
| SCHEMBL1801275 | 0.78 | KDM4E (0.35) | KDM4ECDK8ACVR1GAA | |
| SCHEMBL1805254 | 0.77 | GAA (0.36) | KDM4EMAPTGALR3HTTSMN1; SMN2 | |
| SCHEMBL33611 | 0.75 | KDM4E (0.37) | KDM4EMAPTGALR3HTTSMN1; SMN2 | |
| SCHEMBL6938444 | 0.75 | KDM4E (0.40) | KDM4EPKMCDK8ACVR1GAA | |
| Hydrochloric Acid SCHEMBL7113352 | 0.74 | KDM4E (0.36) | KDM4EMAPTGALR3HTTSMN1; SMN2 | |
| SCHEMBL7529939 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351939-A1 | COUPLER/DEVELOPER AND COUPLER/COUPLER HYBRID DYES AND COUPLER/DEVELOPER AND COUPLER/COUPLER HYBRID DYE INTERMEDIATES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002055500-A1 | COUPLER/DEVELOPER AND COUPLER/COUPLER HYBRID DYES AND COUPLER/DEVELOPER AND COUPLER/COUPLER HYBRID DYE INTERMEDIATES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-07-18 | — | — | WO | disclosed |