Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.62 |
| ▸ | HTR2B | P41595 | 5/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.62 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.62 |
| ▸ | DRD1 | P21728 | 1/20 | 0.62 |
| ▸ | DRD4 | P21917 | 1/20 | 0.62 |
| ▸ | DRD5 | P21918 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967485 | 1.00 | HRH1 (0.62) | HRH1HTR2BKCNH2ALDH1A1KMT2A | |
| SCHEMBL652162 | 0.87 | HTR2B (0.68) | HRH1HTR2BKCNH2ALDH1A1KMT2A | |
| SCHEMBL13051513 | 0.87 | HTR2B (0.68) | HRH1HTR2BKCNH2ALDH1A1KMT2A | |
| SCHEMBL652161 | 0.87 | HTR2B (0.68) | HRH1HTR2BKCNH2ALDH1A1KMT2A | |
| SCHEMBL6738335 | 0.84 | TSHR (0.50) | HRH1HTR2BKCNH2ALDH1A1KMT2A | |
| SCHEMBL8506362 | 0.83 | HRH1 (0.62) | HRH1HTR2BKCNH2ALDH1A1KMT2A | |
| SCHEMBL8506363 | 0.83 | HRH1 (0.62) | HRH1HTR2BKCNH2ALDH1A1KMT2A | |
| SCHEMBL19602917 | 0.83 | HRH1 (0.67) | HRH1HTR2BKCNH2ALDH1A1KMT2A | |
| SCHEMBL4999010 | 0.81 | HTR2B (0.55) | HRH1HTR2BKCNH2ALDH1A1KMT2A | |
| SCHEMBL4999007 | 0.81 | HTR2B (0.55) | HRH1HTR2BKCNH2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934313-B1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK AS (DK) | 2003-05-14 | — | — | EP | disclosed |
| US-6004983-A | ANALGESICS; ANTIINFLAMMATORY, ANTIARTHRITIC AND ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DE) | 1999-12-21 | — | — | US | disclosed |
| EP-0934313-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-08-11 | — | — | EP | disclosed |
| EP-0869777-A1 | NOVEL METHOD | NOVO NORDISK A/S (DK) | 1998-10-14 | — | — | EP | disclosed |
| WO-1998015549-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-04-16 | — | — | WO | disclosed |
| WO-1997022338-A1 | NOVEL METHOD | NOVO NORDISK A/S (DK) | 1997-06-26 | — | — | WO | disclosed |