Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.72 |
| ▸ | PPARG | P37231 | 6/20 | 0.66 |
| ▸ | PIM1 | P11309 | 2/20 | 0.57 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.57 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967650 | 1.00 | HPGD (0.72) | HPGDPPARGPIM1PIM2CISD1 | |
| SCHEMBL9121172 | 0.85 | HPGD (0.68) | HPGDPPARGPIM1PIM2CISD1 | |
| SCHEMBL9121178 | 0.85 | HPGD (0.68) | HPGDPPARGPIM1PIM2CISD1 | |
| SCHEMBL6966747 | 0.85 | HPGD (0.69) | HPGDPPARGPIM1PIM2CISD1 | |
| SCHEMBL6966749 | 0.85 | HPGD (0.69) | HPGDPPARGPIM1PIM2CISD1 | |
| SCHEMBL1299214 | 0.84 | HPGD (1.00) | HPGDPPARGPIM1PIM2CISD1 | |
| SCHEMBL1299215 | 0.84 | HPGD (1.00) | HPGDPPARGPIM1PIM2CISD1 | |
| SCHEMBL2260054 | 0.83 | PPARG (0.78) | HPGDPPARGPIM1PIM2CISD1 | |
| SCHEMBL1847035 | 0.83 | PPARG (0.78) | HPGDPPARGPIM1PIM2CISD1 | |
| SCHEMBL5111753 | 0.83 | PPARG (0.78) | HPGDPPARGPIM1PIM2CISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801063-B1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | REDDYS LAB LTD DR (IN) | 2003-01-15 | — | — | EP | claimed |