SCHEMBL6967693

SCHEMBL6967693

COc1ccc2c(c1)O/C(=C\c1ccc(OC)c(C)c1)C2=O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.74
PTGS2 P35354 1/20 0.66
RAB9A P51151 3/20 0.63
STK17B O94768 2/20 0.63
PPARG P37231 2/20 0.62
PPARD Q03181 2/20 0.62
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
CSNK2A2 P19784 1/20 0.62
CSNK2B P67870 1/20 0.62
CSNK2A1 P68400 1/20 0.62
POLB P06746 1/20 0.62
KIT P10721 1/20 0.61
KDM4E B2RXH2 2/20 0.61
NPC1 O15118 2/20 0.61
MAPT P10636 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
PPARA Q07869 1/20 0.61
GAA P10253 1/20 0.60
RECQL P46063 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6967695 1.00 MAOB (0.74) MAOBPTGS2RAB9ASTK17BPPARG
SCHEMBL6969324 0.90 MAOB (0.60) MAOBPTGS2RAB9ASTK17BPPARG
SCHEMBL6969322 0.90 MAOB (0.60) MAOBPTGS2RAB9ASTK17BPPARG
SCHEMBL6956440 0.89 MEN1 (0.65) MAOBPTGS2RAB9ASTK17BPPARG
SCHEMBL6956439 0.89 MEN1 (0.65) MAOBPTGS2RAB9ASTK17BPPARG
SCHEMBL6963349 0.87 MEN1 (0.77) MAOBPTGS2RAB9ASTK17BMEN1
SCHEMBL6963353 0.87 MEN1 (0.77) MAOBPTGS2RAB9ASTK17BMEN1
SCHEMBL6963414 0.86 MEN1 (0.63) MAOBPTGS2STK17BPPARGPPARD
SCHEMBL6963412 0.86 MEN1 (0.63) MAOBPTGS2STK17BPPARGPPARD
SCHEMBL23066258 0.85 PPARD (0.79) MAOBPTGS2PPARGPPARDCSNK2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0902022-B1 NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME DAIICHI SEIYAKU CO (JP) 2003-07-30 EP disclosed
US-6143779-A Benzofuranone derivatives and a method for producing them SNOW BRAND MILK PRODUCTS CO., LTD. (JP) 2000-11-07 US disclosed
EP-0902022-A1 NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME SNOW BRAND MILK PRODUCTS CO., LTD. (JP) 1999-03-17 EP disclosed