Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968563 | 0.79 | SMN1; SMN2 (0.32) | ALDH1A1MEN1KMT2A | |
| SCHEMBL17512249 | 0.78 | AKT1 (0.41) | MEN1KMT2A | |
| SCHEMBL9740779 | 0.75 | — | — | |
| SCHEMBL13335937 | 0.75 | — | — | |
| SCHEMBL11650236 | 0.75 | KDM7A (0.33) | KDM7APHF8KDM2A | |
| SCHEMBL28079837 | 0.70 | MGAM (0.39) | ALDH1A1MEN1KMT2A | |
| SCHEMBL11784025 | 0.70 | AKT1 (0.33) | MEN1KMT2A | |
| SCHEMBL11797946 | 0.69 | HTT (0.40) | — | |
| SCHEMBL27747541 | 0.67 | — | — | |
| SCHEMBL6754749 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218372-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2003-07-02 | — | — | EP | claimed |