Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8180586 | 0.99 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1TP53MLLT1 | |
| SCHEMBL9039593 | 0.99 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1TP53MLLT1 | |
| Hydrochloric Acid SCHEMBL9212469 | 0.97 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9ANPC1TP53MLLT1 | |
| Bromide SCHEMBL6961358 | 0.97 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9ANPC1TP53MLLT1 | |
| SCHEMBL9039113 | 0.87 | MEN1 (0.48) | SMN1; SMN2RAB9ANPC1TP53MLLT1 | |
| Hydrochloric Acid SCHEMBL9221658 | 0.86 | MEN1 (0.47) | SMN1; SMN2RAB9ANPC1TP53MLLT1 | |
| SCHEMBL8180687 | 0.86 | MEN1 (0.47) | SMN1; SMN2RAB9ANPC1TP53MLLT1 | |
| Bromide SCHEMBL6967598 | 0.86 | MEN1 (0.47) | SMN1; SMN2RAB9ANPC1TP53MLLT1 | |
| SCHEMBL4317299 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9ANPC1TP53MLLT1 | |
| Hydrochloric Acid SCHEMBL6962238 | 0.85 | MEN1 (0.46) | SMN1; SMN2RAB9ANPC1TP53MLLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071746-C | Amidine derivatives with nitric oxide synthetase activities | ASTERA CO (SE) | 2001-09-26 | — | — | CN | claimed |
| CN-1132505-A | Amidine derivatives with nitric oxide synthetase activities | ASTERA CO (SE) | 1996-10-02 | — | — | CN | claimed |
| EP-0713483-A1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | Astra Aktiebolag (SE) | 1996-05-29 | — | — | EP | claimed |
| WO-1995005363-A1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | ASTRA AKTIEBOLAG (SE) | 1995-02-23 | — | — | WO | claimed |
| EP-0713483-B1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | ASTRAZENECA AB (SE) | 2003-01-15 | — | — | EP | disclosed |
| CN-1071746-C | Amidine derivatives with nitric oxide synthetase activities | ASTERA CO (SE) | 2001-09-26 | — | — | CN | disclosed |
| CN-1132505-A | Amidine derivatives with nitric oxide synthetase activities | ASTERA CO (SE) | 1996-10-02 | — | — | CN | disclosed |