Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 10/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | LIPE | Q05469 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29381931 | 1.00 | SCD (0.44) | SCDUSP30ACACBLIPESCN9A | |
| SCHEMBL84052 | 0.94 | SCD (0.44) | SCDUSP30LIPESCN9A | |
| SCHEMBL70508 | 0.87 | EPHX2 (0.49) | SCDUSP30LIPE | |
| SCHEMBL29384487 | 0.87 | EPHX2 (0.49) | SCDUSP30LIPE | |
| SCHEMBL69698 | 0.86 | SCD (0.59) | SCDUSP30 | |
| SCHEMBL70183 | 0.86 | USP30 (0.42) | SCDUSP30LIPESCN9A | |
| SCHEMBL29382319 | 0.84 | USP30 (0.44) | SCDUSP30 | |
| SCHEMBL69037 | 0.84 | USP30 (0.44) | SCDUSP30 | |
| SCHEMBL70477 | 0.81 | SCD (0.46) | SCDACACBLIPE | |
| SCHEMBL29385049 | 0.81 | SCD (0.46) | SCDACACBLIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268143-A2 | NOVEL PIPERIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | Forest Laboratories Holdings Limited (BM) | 2011-01-05 | — | — | EP | claimed |
| EP-2268143-A2 | NOVEL PIPERIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | Forest Laboratories Holdings Limited (BM) | 2011-01-05 | — | — | EP | disclosed |