Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 4/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | KIT | P10721 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969478 | 1.00 | MEN1 (0.67) | MEN1KMT2AUSP2RECQLMAOB | |
| SCHEMBL6957789 | 0.91 | MAOB (0.78) | MEN1KMT2ARECQLMAOBPTGS2 | |
| SCHEMBL6957794 | 0.91 | MAOB (0.78) | MEN1KMT2ARECQLMAOBPTGS2 | |
| SCHEMBL6963133 | 0.90 | MEN1 (0.71) | MEN1KMT2AUSP2RECQLMAOB | |
| SCHEMBL6963130 | 0.90 | MEN1 (0.71) | MEN1KMT2AUSP2RECQLMAOB | |
| SCHEMBL6967079 | 0.88 | MEN1 (0.65) | MEN1KMT2AUSP2MAOBPTGS2 | |
| SCHEMBL6967086 | 0.88 | MEN1 (0.65) | MEN1KMT2AUSP2MAOBPTGS2 | |
| SCHEMBL6964652 | 0.88 | MAOB (0.66) | MEN1KMT2ARECQLMAOBPTGS2 | |
| SCHEMBL6964657 | 0.88 | MAOB (0.66) | MEN1KMT2ARECQLMAOBPTGS2 | |
| SCHEMBL6968908 | 0.87 | MEN1 (0.70) | MEN1KMT2AUSP2MAOBPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902022-B1 | NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | DAIICHI SEIYAKU CO (JP) | 2003-07-30 | — | — | EP | disclosed |
| US-6143779-A | Benzofuranone derivatives and a method for producing them | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0902022-A1 | NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 1999-03-17 | — | — | EP | disclosed |