Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969863 | 1.00 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1RAB9ANPC1KDM4E | |
| SCHEMBL30530488 | 0.87 | CYSLTR1 (0.57) | CYSLTR2CYSLTR1RAB9ANPC1KDM4E | |
| SCHEMBL919522 | 0.87 | CYSLTR1 (0.57) | CYSLTR2CYSLTR1RAB9ANPC1KDM4E | |
| SCHEMBL919524 | 0.87 | CYSLTR1 (0.57) | CYSLTR2CYSLTR1RAB9ANPC1KDM4E | |
| SCHEMBL10421429 | 0.84 | KDM4E (0.65) | CYSLTR2CYSLTR1RAB9ANPC1KDM4E | |
| SCHEMBL10421430 | 0.84 | KDM4E (0.65) | CYSLTR2CYSLTR1RAB9ANPC1KDM4E | |
| SCHEMBL6750524 | 0.84 | KDM4E (0.67) | CYSLTR2CYSLTR1RAB9ANPC1KDM4E | |
| SCHEMBL8306853 | 0.82 | CYSLTR1 (0.45) | CYSLTR2CYSLTR1RAB9ANPC1KDM4E | |
| SCHEMBL8306852 | 0.82 | CYSLTR1 (0.45) | CYSLTR2CYSLTR1RAB9ANPC1KDM4E | |
| SCHEMBL3748357 | 0.81 | CCR1 (0.48) | CYSLTR2CYSLTR1RAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902007-B1 | CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2003-11-05 | — | — | EP | disclosed |
| US-6046212-A | ANTIALLERGIC AGENTS | KOWA CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0902007-A1 | CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1999-03-17 | — | — | EP | disclosed |