SCHEMBL6970075

SCHEMBL6970075

CCOC(=O)c1ccc(O)c(C(C)=O)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.70
CA1 P00915 6/20 0.70
CA2 P00918 6/20 0.70
CA7 P43166 6/20 0.70
CA9 Q16790 6/20 0.70
CA14 Q9ULX7 6/20 0.70
HSD17B2 P37059 1/20 0.62
ESR1 P03372 1/20 0.56
ESR2 Q92731 1/20 0.56
KMT2A Q03164 3/20 0.53
HSD17B10 Q99714 3/20 0.53
HPGD P15428 2/20 0.53
MEN1 O00255 2/20 0.53
TP53 P04637 2/20 0.53
ALDH1A1 P00352 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
LMNA P02545 3/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAOA P21397 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10570974 0.90 CA12 (0.74) CA12CA1CA2CA7CA9
SCHEMBL398849 0.87 CA12 (0.70) CA12CA1CA2CA7CA9
SCHEMBL4503294 0.87 CA12 (0.70) CA12CA1CA2CA7CA9
SCHEMBL3893649 0.87 CA12 (0.68) CA12CA1CA2CA7CA9
SCHEMBL403798 0.85 CA1 (0.68) CA12CA1CA2CA7CA9
SCHEMBL13179070 0.83 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL7013424 0.83 CA12 (0.64) CA12CA1CA2CA7CA9
SCHEMBL29625511 0.82 CA12 (1.00) CA12CA1CA2CA7CA9
SCHEMBL39791 0.82 CA12 (1.00) CA12CA1CA2CA7CA9
SCHEMBL29403559 0.82 CA12 (0.66) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210171883-A1 ANTIVIRAL WIPER FUJIFILM CORPORATION (JP) 2021-06-10 US disclosed
EP-0902007-B1 CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME KOWA CO (JP) 2003-11-05 EP disclosed
EP-0902007-A1 CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME KOWA CO. LTD. (JP) 1999-03-17 EP disclosed
US-4148900-A ANTIALLERGIC CARLO ERBA S.P.A. (IT) 1979-04-10 US disclosed
US-4115567-A TREATMENT OF ALLERGIES CARLO ERBA S. P. A. (IT) 1978-09-19 US disclosed
US-4083953-A ANTIALLERGENS CARLO ERBA, S.P.A. (IT) 1978-04-11 US disclosed
US-4065467-A ANTIALLERGENS, ANTIULCER AGENTS, TREATMENT OF RESPIRATORY SYSTEM AND PULMONARY DISORDERS CARLO ERBA, S. P. A. (IT) 1977-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210171883-A1 ANTIVIRAL WIPER CGAS, PRKX, PDE4C CA12 2396/4885CA1 2414/4885CA2 1789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.