Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.45 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960230 | 0.93 | EPHX2 (0.49) | EPHX2MMP12PARP10PARP11PARP1 | |
| SCHEMBL30509208 | 0.81 | EPHX2 (0.51) | EPHX2MMP12BRD4CREBBPCSNK1G1 | |
| SCHEMBL11455059 | 0.81 | EPHX2 (0.51) | EPHX2MMP12BRD4CREBBPCSNK1G1 | |
| SCHEMBL19203466 | 0.79 | CA9 (0.59) | ALDH1A1MAPTGAASMN1; SMN2NPC1 | |
| SCHEMBL29126120 | 0.79 | PARP1 (0.45) | PARP10PARP1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL30697324 | 0.79 | PARP1 (0.45) | PARP10PARP1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL6959254 | 0.79 | AHR (0.51) | PARP10PARP1MAPTCYP1A2CYP2C19 | |
| SCHEMBL30832124 | 0.79 | CMA1 (0.51) | PARP10PARP11PARP1BRD4CRBN | |
| SCHEMBL6968312 | 0.78 | PDE3B (0.53) | ALDH1A1MAPTCYP1A2CYP2C19NPC1 | |
| SCHEMBL10274620 | 0.77 | EPHX2 (0.55) | EPHX2MMP12BRD4CREBBPCSNK1G1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |