⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23717757 | 0.80 | — | — | |
| SCHEMBL11416731 | 0.77 | — | — | |
| SCHEMBL5463320 | 0.77 | — | — | |
| SCHEMBL234815 | 0.76 | — | — | |
| SCHEMBL27674882 | 0.74 | — | — | |
| SCHEMBL1568646 | 0.74 | — | — | |
| SCHEMBL7799813 | 0.74 | — | — | |
| SCHEMBL13793950 | 0.74 | — | — | |
| SCHEMBL6970654 | 0.73 | — | — | |
| SCHEMBL3084079 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212120-A1 | SMALL MOLECULE INHIBITORS OF GRK5 AND GRK5 SUBFAMILY MEMBERS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2023-07-06 | — | — | US | disclosed |
| US-10016512-B2 | Immobilised biological entities | CARMEDA AB (SE) | 2018-07-10 | — | — | US | disclosed |
| US-20180140713-A1 | IMMOBILISED BIOLOGICAL ENTITIES | CARMEDA AB (SE) | 2018-05-24 | — | — | US | disclosed |
| US-20170368237-A1 | IMMOBILISED BIOLOGICAL ENTITIES | GORE & ASS (US) | 2017-12-28 | — | — | US | disclosed |
| US-9764068-B2 | Immobilised biological entities | W.L. GORE AND ASSOCIATES INC. (US) | 2017-09-19 | — | — | US | disclosed |
| US-20160310646-A1 | IMMOBILISED BIOLOGICAL ENTITIES | W. L. GORE & ASSOCIATES, INC. | 2016-10-27 | — | — | US | disclosed |
| US-20160228572-A9 | Immobilised Biological Entities | CARMEDA AB (SE) | 2016-08-11 | — | — | US | disclosed |
| US-9408950-B2 | Immobilised biological entities | W.L. GORE & ASSOCIATES, INC. (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150367040-A1 | IMMOBILISED BIOLOGICAL ENTITIES | GORE ENTERPRISE HOLDINGS, INC. | 2015-12-24 | — | — | US | disclosed |
| US-9101696-B2 | Immobilised biological entities | W.L. GORE & ASSOCIATES, INC. (US) | 2015-08-11 | — | — | US | disclosed |
| US-20130273122-A1 | Immobilised Biological Entities | CARMEDA AB (SE) | 2013-10-17 | — | — | US | disclosed |
| US-8501212-B2 | Immobilised biological entities | CARMEDA AB (SE) | 2013-08-06 | — | — | US | disclosed |
| US-20120288935-A1 | \"Click\" Nanoparticle Conjugates | NORTHWESTERN UNIVERSITY (US) | 2012-11-15 | — | — | US | disclosed |
| US-20120231043-A1 | IMMOBILISED BIOLOGICAL ENTITIES | CARMEDA AB (SE) | 2012-09-13 | — | — | US | disclosed |
| US-20110223229-A1 | IMMOBILISED BIOLOGICAL ENTITIES | CARMEDA AB (SE) | 2011-09-15 | — | — | US | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |