Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469510 | 0.83 | PDE10A (0.53) | PDE10APOLBFFAR1ALDH1A1CYP1A2 | |
| SCHEMBL126343 | 0.81 | PDE10A (0.51) | PDE10APOLBFFAR1ALDH1A1CYP1A2 | |
| SCHEMBL30832623 | 0.81 | PDE10A (0.51) | PDE10APOLBFFAR1ALDH1A1CYP1A2 | |
| SCHEMBL6453136 | 0.76 | FFAR1 (0.49) | PDE10APOLBFFAR1ALDH1A1CYP1A2 | |
| SCHEMBL3952124 | 0.75 | PDE10A (0.45) | PDE10APOLBFFAR1ALDH1A1CYP1A2 | |
| SCHEMBL3952121 | 0.75 | PDE10A (0.45) | PDE10APOLBFFAR1ALDH1A1CYP1A2 | |
| SCHEMBL43627 | 0.75 | PDE10A (0.56) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL29940575 | 0.74 | PDE10A (0.60) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL6512953 | 0.74 | PDE10A (0.60) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8372498 | 0.74 | PDE10A (0.47) | PDE10APOLBALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |