Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 20/20 | 0.98 |
| ▸ | CCNE1 | P24864 | 20/20 | 0.98 |
| ▸ | CDK2 | P24941 | 20/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971130 | 1.00 | CCNE2 (0.98) | CCNE2CCNE1CDK2 | |
| Hydrochloric Acid SCHEMBL6979092 | 0.99 | CCNE2 (1.00) | CCNE2CCNE1CDK2 | |
| Hydrochloric Acid SCHEMBL6979102 | 0.99 | CCNE2 (1.00) | CCNE2CCNE1CDK2 | |
| SCHEMBL6975212 | 0.95 | CCNE2 (0.89) | CCNE2CCNE1CDK2 | |
| SCHEMBL6975220 | 0.95 | CCNE2 (0.89) | CCNE2CCNE1CDK2 | |
| Hydrochloric Acid SCHEMBL6966198 | 0.94 | CCNE2 (0.90) | CCNE2CCNE1CDK2 | |
| Hydrochloric Acid SCHEMBL6966184 | 0.94 | CCNE2 (0.90) | CCNE2CCNE1CDK2 | |
| SCHEMBL6976110 | 0.93 | CCNE2 (0.85) | CCNE2CCNE1CDK2 | |
| SCHEMBL6976112 | 0.93 | CCNE2 (0.85) | CCNE2CCNE1CDK2 | |
| SCHEMBL6978398 | 0.90 | CCNE2 (1.00) | CCNE2CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157019-B1 | 4-ALKENYL (AND ALKYNYL) OXINDOLES AS INHIBITORS OF CYCLIN-DEPENDENT KINASES, IN PARTICULAR CDK2 | HOFFMANN LA ROCHE (CH) | 2003-03-19 | — | — | EP | claimed |