SCHEMBL6971176

SCHEMBL6971176

[O]C(=O)NC(=O)C(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6971181 0.75
SCHEMBL6963759 0.73
SCHEMBL6963765 0.73
SCHEMBL6967313 0.69
SCHEMBL29086003 0.67
SCHEMBL9849006 0.67
SCHEMBL6963670 0.65
SCHEMBL2447843 0.65
SCHEMBL9024582 0.65
SCHEMBL487015 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP disclosed
CN-1124737-A Method for production of t-butyl 3-oxobutyrates and their use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1996-06-19 CN disclosed
US-5183929-A Method for production of T-butyl 3-oxobutyrates and their use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-02-02 US disclosed
US-5109131-A METHOD FOR PRODUCTION OF T-BUTYL 3-OXOBUTYRATES AND THEIR USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-04-28 US disclosed
CN-1035283-A Process for producing tert-butyl 3-oxobutyrate and use thereof TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1989-09-06 CN disclosed
US-4680390-A CEPHALOSPORINS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1987-07-14 US disclosed
US-4520194-A BACTERICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1985-05-28 US disclosed
US-4510138-A 7-[2-(2-Aminothiazol-4-yl)-2-(syn)-methoxyiminoacetamido]cephalosporin derivatives TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1985-04-09 US disclosed
US-4278671-A ANTIBIOTICS, BACTERICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1981-07-14 US disclosed