Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741531 | 0.80 | NPSR1 (0.50) | NPSR1ALDH1A1TSHRKMT2APOLB | |
| SCHEMBL6960658 | 0.78 | NPSR1 (0.48) | NPSR1ALDH1A1TSHRKMT2APOLB | |
| SCHEMBL8396656 | 0.76 | NPSR1 (0.46) | NPSR1ALDH1A1TSHRKMT2APOLB | |
| SCHEMBL1635424 | 0.76 | NPSR1 (0.46) | NPSR1ALDH1A1TSHRKMT2APOLB | |
| SCHEMBL16586083 | 0.76 | NPSR1 (0.46) | NPSR1ALDH1A1TSHRKMT2APOLB | |
| SCHEMBL8396658 | 0.76 | NPSR1 (0.46) | NPSR1ALDH1A1TSHRKMT2APOLB | |
| SCHEMBL6611160 | 0.76 | NPSR1 (0.41) | NPSR1ALDH1A1TSHRKMT2APOLB | |
| SCHEMBL245524 | 0.76 | NPSR1 (0.41) | NPSR1ALDH1A1TSHRKMT2APOLB | |
| SCHEMBL6611167 | 0.76 | AKT1 (0.43) | NPSR1ALDH1A1TSHRKMT2APOLB | |
| SCHEMBL1176964 | 0.75 | NPSR1 (0.64) | NPSR1ALDH1A1TSHRKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |