Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.58 |
| ▸ | PPARA | Q07869 | 17/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034034 | 0.89 | KDR (0.65) | PPARGPPARAFFAR1KDR | |
| SCHEMBL6957438 | 0.86 | PPARG (0.55) | PPARGPPARAFFAR1KDR | |
| SCHEMBL6970901 | 0.85 | PPARG (0.54) | PPARGPPARAFFAR1KDR | |
| SCHEMBL6156850 | 0.85 | FFAR1 (0.74) | PPARGPPARAFFAR1KDR | |
| SCHEMBL4031358 | 0.84 | PPARG (0.56) | PPARGPPARAFFAR1KDR | |
| SCHEMBL6964583 | 0.84 | PPARG (0.57) | PPARGPPARAFFAR1 | |
| SCHEMBL6965619 | 0.83 | PPARG (0.49) | PPARGPPARAFFAR1 | |
| SCHEMBL6959844 | 0.83 | PPARG (0.49) | PPARGPPARAFFAR1 | |
| SCHEMBL6962848 | 0.81 | FFAR1 (0.71) | PPARGPPARAFFAR1KDR | |
| SCHEMBL5738174 | 0.81 | PPARG (0.72) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629624-B1 | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-5591862-A | ANTILIPEMICS, TREATING DIABETES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0629624-A1 | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-21 | — | — | EP | disclosed |