Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8989516 | 0.83 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C19RAB9AHPGD | |
| SCHEMBL1926743 | 0.82 | SMN1; SMN2 (0.52) | CYP1A2CYP3A4CYP2C19RAB9AHPGD | |
| SCHEMBL16771241 | 0.81 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C19RAB9AHPGD | |
| SCHEMBL769495 | 0.81 | CYP1A2 (0.61) | CYP1A2CYP3A4CYP2C19RAB9AHPGD | |
| SCHEMBL3368984 | 0.81 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C19RAB9AHPGD | |
| SCHEMBL6965934 | 0.79 | CYP1A2 (0.38) | CYP1A2CYP3A4CYP2C19RAB9AHPGD | |
| SCHEMBL14032969 | 0.79 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C19RAB9AHPGD | |
| SCHEMBL14051590 | 0.79 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C19RAB9AHPGD | |
| SCHEMBL11360493 | 0.79 | SMN1; SMN2 (0.71) | CYP1A2CYP3A4CYP2C19RAB9AHPGD | |
| SCHEMBL17069263 | 0.77 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C19RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |