Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.38 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2103632 | 0.79 | LRRK2 (0.36) | — | |
| SCHEMBL1451106 | 0.75 | KDM4E (0.31) | — | |
| SCHEMBL2103875 | 0.73 | AR (0.34) | — | |
| SCHEMBL232460 | 0.73 | — | — | |
| SCHEMBL408050 | 0.72 | TSHR (0.33) | TSHR | |
| SCHEMBL2038335 | 0.71 | — | — | |
| SCHEMBL1343863 | 0.71 | KDM4E (0.52) | ROCK2ROCK1CDC42BPACDC42BPBTSHR | |
| SCHEMBL29565140 | 0.71 | KDM4E (0.52) | ROCK2ROCK1CDC42BPACDC42BPBTSHR | |
| SCHEMBL1818357 | 0.70 | — | — | |
| SCHEMBL1099658 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |