SCHEMBL6971651

SCHEMBL6971651

CCCCC[CH]C(=O)OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.53
ALDH1A1 P00352 4/20 0.52
MAPK1 P28482 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
CYP3A4 P08684 1/20 0.52
TSHR P16473 1/20 0.52
CETP P11597 3/20 0.50
LMNA P02545 1/20 0.50
AKR1B10 O60218 2/20 0.47
AKR1B1 P15121 2/20 0.47
CA12 O43570 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
CA5A P35218 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47
CA5B Q9Y2D0 1/20 0.47
EPHX2 P34913 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8895871 0.98 CETP (0.52) HCAR2ALDH1A1MAPK1TDP1L3MBTL1
SCHEMBL8897560 0.98 CETP (0.52) HCAR2ALDH1A1MAPK1TDP1L3MBTL1
SCHEMBL9346153 0.98 CETP (0.52) HCAR2ALDH1A1MAPK1TDP1L3MBTL1
SCHEMBL6966475 0.95 HCAR2 (0.54) HCAR2ALDH1A1MAPK1TDP1L3MBTL1
SCHEMBL6708209 0.89 HCAR2 (0.57) HCAR2ALDH1A1MAPK1TDP1L3MBTL1
SCHEMBL8894320 0.88 TSHR (0.42) HCAR2ALDH1A1MAPK1TDP1L3MBTL1
SCHEMBL14675315 0.84 HCAR2 (0.53) HCAR2ALDH1A1MAPK1TDP1L3MBTL1
SCHEMBL14871736 0.84 HCAR2 (0.56) HCAR2ALDH1A1MAPK1TDP1L3MBTL1
SCHEMBL29196901 0.84 HCAR2 (0.56) HCAR2ALDH1A1MAPK1TDP1L3MBTL1
SCHEMBL6133091 0.82 HCAR2 (0.61) HCAR2ALDH1A1MAPK1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP disclosed
US-5670563-A ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND CIBA-SPECIALTY CHEMICALS CORPORATION (US) 1997-09-23 US disclosed
EP-0219154-B1 FURYL COMPOUNDS, THEIR USE AS FUNGICIDES AND THEIR PREPARATION SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-11-13 EP disclosed