SCHEMBL69719

SCHEMBL69719

Cc1ccc2c(c1)C(=O)C(C)O2

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.46
ACHE P22303 1/20 0.44
TSHR P16473 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.42
BRD4 O60885 1/20 0.41
CREBBP Q92793 1/20 0.41
ESR1 P03372 1/20 0.41
MAOB P27338 6/20 0.39
MAOA P21397 1/20 0.39
ELANE P08246 1/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HTT P42858 1/20 0.37
ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30576378 1.00 CYP19A1 (0.46) CYP19A1ACHETSHRNPSR1RAB9A
SCHEMBL11108271 0.81 ESR1 (0.49) CYP19A1ACHETSHRNPSR1RAB9A
SCHEMBL31426217 0.79 PBRM1 (0.58) CYP19A1KMT2AESR1KDM4EALDH1A1
SCHEMBL12194215 0.79 P2RY6 (0.45) TSHRNPSR1RAB9AKMT2AESR1
SCHEMBL69706 0.79 CYP19A1 (0.45) CYP19A1ACHERAB9AKMT2ABRD4
SCHEMBL69705 0.79 CYP19A1 (0.45) CYP19A1TSHRESR1MAOBALDH1A1
SCHEMBL3601355 0.79 PBRM1 (0.58) CYP19A1KMT2AESR1KDM4EALDH1A1
SCHEMBL8312445 0.78 CYP19A1 (0.44) CYP19A1ACHERAB9AKMT2ABRD4
SCHEMBL18533326 0.77 TSHR (0.36) CYP19A1ACHETSHRNPSR1RAB9A
SCHEMBL12180433 0.75 TDP1 (0.50) TSHRRAB9AKMT2AESR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3865480-B1 HYDRAZINE DERIVATIVES FMC CORP (US) 2025-11-05 EP disclosed
CN-111018790-B Pyridazinone herbicides FMC公司 2023-09-19 CN disclosed
EP-3865480-A1 HYDRAZINE DERIVATIVES FMC Corporation (US) 2021-08-18 EP disclosed
EP-3137456-B1 PYRIDAZINONE HERBICIDES FMC CORP (US) 2021-06-02 EP disclosed
CN-111018790-A Pyridazinone herbicides FMC公司 2020-04-17 CN disclosed
US-10597388-B2 Pyridazinone herbicides FMC CORPORATION (US) 2020-03-24 US disclosed
CN-106458926-B Pyridazinone herbicides FMC公司 2020-01-03 CN disclosed
US-20190016712-A1 PYRIDAZINONE HERBICIDES FMC CORPORATION 2019-01-17 US disclosed
US-10118917-B2 Pyridazinone herbicides FMC CORPORATION 2018-11-06 US disclosed
EP-3137456-A1 PYRIDAZINONE HERBICIDES E. I. du Pont de Nemours and Company (US) 2017-03-08 EP disclosed
EP-2042573-A1 Ink composition FUJIFILM Corporation (JP) 2009-04-01 EP disclosed
EP-2042563-A1 Photocurable coating composition, and overprint and process for producing same FUJIFILM Corporation (JP) 2009-04-01 EP disclosed
US-20090081421-A1 PHOTOCURABLE COATING COMPOSITION, AND OVERPRINT AND PROCESS FOR PRODUCING SAME FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
US-20090081421-A1 PHOTOCURABLE COATING COMPOSITION, AND OVERPRINT AND PROCESS FOR PRODUCING SAME FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
US-20080239045-A1 INK SET FOR INKJET RECORDING AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080239045-A1 INK SET FOR INKJET RECORDING AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
EP-1975210-A1 Ink set for inkjet recording and inkjet recording method FUJIFILM Corporation (JP) 2008-10-01 EP disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
EP-1944173-A1 Ink composition and inkjet recording method using the same FUJIFILM Corporation (JP) 2008-07-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190016712-A1 PYRIDAZINONE HERBICIDES CBR3, NOX5, NR5A2 CYP19A1 583/4885ACHE 428/4885TSHR 769/4885
US-10118917-B2 Pyridazinone herbicides CBR3, NOX5, NR5A2 CYP19A1 583/4885ACHE 428/4885TSHR 769/4885
US-10597388-B2 Pyridazinone herbicides CBR3, NOX5, NR5A2 CYP19A1 583/4885ACHE 428/4885TSHR 769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.