Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 4/20 | 0.32 |
| ▸ | CES1 | P23141 | 4/20 | 0.32 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957918 | 0.94 | POLB (0.32) | CES2GMNNTP53POLBMAPT | |
| SCHEMBL6965922 | 0.85 | — | — | |
| SCHEMBL625145 | 0.83 | POLB (0.53) | CES2GMNNTP53POLBMAPT | |
| SCHEMBL6957924 | 0.77 | POLB (0.50) | CES2GMNNTP53POLBMAPT | |
| SCHEMBL11870679 | 0.74 | TSHR (0.41) | MAPTTSHR | |
| Bicarbonate SCHEMBL9835481 | 0.74 | TSHR (0.45) | MAPTCYP2C9HSD17B10TSHR | |
| Bicarbonate SCHEMBL2169350 | 0.74 | TSHR (0.45) | MAPTCYP2C9HSD17B10TSHR | |
| Bicarbonate SCHEMBL11744374 | 0.71 | TSHR (0.43) | MAPTCYP2C9HSD17B10TSHR | |
| SCHEMBL6593404 | 0.70 | — | — | |
| SCHEMBL6965014 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |