⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972244 | 0.79 | — | — | |
| SCHEMBL3031693 | 0.79 | CDC7 (0.45) | — | |
| SCHEMBL3021513 | 0.78 | — | — | |
| SCHEMBL27595291 | 0.76 | RPS6KA3 (0.38) | — | |
| SCHEMBL22303890 | 0.75 | RPS6KA3 (0.47) | — | |
| SCHEMBL22020750 | 0.73 | RPS6KA3 (0.43) | — | |
| SCHEMBL8554906 | 0.73 | — | — | |
| SCHEMBL6968298 | 0.71 | — | — | |
| Formic Acid SCHEMBL27595292 | 0.71 | RPS6KA3 (0.40) | — | |
| SCHEMBL22302811 | 0.71 | RPS6KA3 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102807568-B | Thiadiazoles derivative class DPP-IV inhibitor | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2015-11-25 | — | — | CN | disclosed |
| CN-102807568-A | Thiadiazole derivative DPP-IV (dipeptidyl peptidase IV) inhibitor | JIANGSU CHIA TAI TIANQING PHAR | 2012-12-05 | — | — | CN | disclosed |
| CN-101273029-A | Bicyclic bisamide derivatives and their use as pesticides | SYNGENTA PARTICIPATIONS AG (CH) | 2008-09-24 | — | — | CN | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| CN-1333754-A | Benzoheterocycles and their use as MEK inhibitors | WARNER LAMBERT CO (US) | 2002-01-30 | — | — | CN | disclosed |
| US-5173496-A | Antiinflammatory agents | ICI PHARMA (FR) | 1992-12-22 | — | — | US | disclosed |
| EP-0284174-B1 | THERAPEUTIC PREPARATIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-29 | — | — | EP | disclosed |
| EP-0284174-A1 | Therapeutic preparations | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-28 | — | — | EP | disclosed |