Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 9/20 | 0.63 |
| ▸ | NQO1 | P15559 | 1/20 | 0.60 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9406598 | 0.87 | TLR8 (0.57) | NQO2NQO1TLR8RAD52UHRF1 | |
| SCHEMBL31124812 | 0.87 | NQO2 (0.56) | NQO2NQO1TLR8RAD52UHRF1 | |
| SCHEMBL384865 | 0.83 | NQO2 (0.55) | NQO2NQO1TLR8RAD52UHRF1 | |
| SCHEMBL5796954 | 0.82 | RAD52 (0.54) | NQO2NQO1TLR8RAD52UHRF1 | |
| SCHEMBL2945567 | 0.81 | MEN1 (0.50) | NQO2NQO1TLR8RAD52UHRF1 | |
| SCHEMBL5799064 | 0.81 | RAD52 (0.56) | NQO2TLR8RAD52UHRF1MEN1 | |
| SCHEMBL240664 | 0.80 | NQO2 (0.57) | NQO2NQO1TLR8RAD52KMT2A | |
| SCHEMBL30228371 | 0.80 | NQO2 (0.67) | NQO2TLR8MEN1KMT2ANPC1 | |
| SCHEMBL6239156 | 0.80 | NQO2 (0.67) | NQO2TLR8MEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL15271481 | 0.79 | NQO2 (0.56) | NQO2NQO1TLR8RAD52KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107904201-A | Differentiation of the human embryo stem cell to pancreatic endocrine pedigree | 詹森生物科技公司 | 2018-04-13 | — | — | CN | claimed |
| CN-107904201-A | Differentiation of the human embryo stem cell to pancreatic endocrine pedigree | 詹森生物科技公司 | 2018-04-13 | — | — | CN | disclosed |
| EP-1200434-B1 | NEW CYTOTOXIC PYRIDO 2,3,4-kl]ACRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | UNIV BARCELONA (ES) | 2003-05-14 | — | — | EP | disclosed |
| US-6559161-B1 | Method for treating a mammal affected by a malignant tumour, which comprises administering to a mammal in need of such treatment a therapeutically effective amount of a compound of formula (I), a pharmaceutically acceptable salt | UNIVERSIDAD DE BARCELONA (ES) | 2003-05-06 | — | — | US | disclosed |