Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | PRCP | P42785 | 3/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5898614 | 0.86 | NPSR1 (0.61) | NPSR1PRCPNAAAPOLBTSHR | |
| SCHEMBL9280388 | 0.86 | NPSR1 (0.61) | NPSR1PRCPNAAAPOLBTSHR | |
| SCHEMBL21091374 | 0.86 | NPSR1 (0.61) | NPSR1PRCPNAAAPOLBTSHR | |
| SCHEMBL11435886 | 0.84 | NPSR1 (0.56) | NPSR1PRCPNAAAPOLBTSHR | |
| SCHEMBL6242559 | 0.83 | NPSR1 (0.55) | NPSR1PRCPNAAAPOLBTSHR | |
| SCHEMBL6244947 | 0.83 | NPSR1 (0.55) | NPSR1PRCPNAAAPOLBTSHR | |
| SCHEMBL9277176 | 0.82 | NPSR1 (0.57) | NPSR1PRCPNAAAPOLBTSHR | |
| SCHEMBL9277170 | 0.82 | NPSR1 (0.57) | NPSR1PRCPNAAAPOLBTSHR | |
| SCHEMBL9279791 | 0.81 | NPSR1 (0.56) | NPSR1PRCPNAAAPOLBTSHR | |
| SCHEMBL9275048 | 0.81 | NPSR1 (0.56) | NPSR1PRCPNAAAPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268418-A1 | PHARMACEUTICALLY ACTIVE PYRROLIDINE DERIVATIVES AS BAX INHIBITORS | Applied Research Systems ARS Holding N.V. (AN) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001074769-A1 | PHARMACEUTICALLY ACTIVE PYRROLIDINE DERIVATIVES AS BAX INHIBITORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-10-11 | — | — | WO | disclosed |