Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 14/20 | 0.59 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.59 |
| ▸ | OXTR | P30559 | 2/20 | 0.56 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961742 | 0.91 | AVPR2 (0.56) | AVPR2AVPR1AOXTRAVPR1BABCB11 | |
| SCHEMBL6962598 | 0.90 | AVPR2 (0.61) | AVPR2AVPR1AOXTRAVPR1BABCB11 | |
| SCHEMBL6965061 | 0.90 | AVPR2 (0.65) | AVPR2AVPR1AOXTRAVPR1BABCB11 | |
| SCHEMBL6965024 | 0.89 | AVPR2 (0.57) | AVPR2AVPR1AOXTRAVPR1BABCB11 | |
| SCHEMBL6966369 | 0.85 | AVPR2 (0.77) | AVPR2AVPR1AOXTRAVPR1BABCB11 | |
| SCHEMBL8961694 | 0.84 | AVPR2 (0.72) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6965154 | 0.82 | AVPR2 (0.56) | AVPR2AVPR1AAVPR1BABCB11HTR1A | |
| SCHEMBL7087152 | 0.81 | AVPR2 (0.71) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6970595 | 0.81 | AVPR2 (0.54) | AVPR2AVPR1AOXTRAVPR1BABCB11 | |
| SCHEMBL7345800 | 0.81 | AVPR2 (0.77) | AVPR2AVPR1AOXTRAVPR1BABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |