⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20499392 | 0.67 | — | — | |
| SCHEMBL20541953 | 0.62 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL21331900 | 0.62 | — | — | |
| SCHEMBL7055927 | 0.55 | — | — | |
| SCHEMBL21385228 | 0.53 | — | — | |
| SCHEMBL446051 | 0.50 | — | — | |
| SCHEMBL8367460 | 0.48 | — | — | |
| SCHEMBL2577997 | 0.46 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL7104332 | 0.45 | — | — | |
| SCHEMBL722089 | 0.45 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |