Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP10 | Q14694 | 1/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2994232 | 0.89 | CYP1A2 (0.50) | CYP1A2TDP1ATMPDK1MAPT | |
| SCHEMBL30410464 | 0.89 | CYP1A2 (0.50) | CYP1A2TDP1ATMPDK1MAPT | |
| SCHEMBL27707665 | 0.87 | TDP1 (0.49) | CYP1A2TDP1ATMPDK1MAPT | |
| SCHEMBL2989578 | 0.84 | CYP1A2 (0.69) | CYP1A2TDP1ATMPDK1MAPT | |
| SCHEMBL2989584 | 0.84 | CYP1A2 (0.69) | CYP1A2TDP1ATMPDK1MAPT | |
| SCHEMBL31235286 | 0.84 | CYP1A2 (0.46) | CYP1A2TDP1ATMMAPTALDH1A1 | |
| SCHEMBL6973098 | 0.84 | CYP1A2 (0.46) | CYP1A2TDP1ATMMAPTALDH1A1 | |
| SCHEMBL2568261 | 0.83 | CYP1A2 (0.48) | CYP1A2TDP1ATMPDK1MAPT | |
| SCHEMBL7594106 | 0.83 | CYP1A2 (0.50) | CYP1A2TDP1ATMPDK1MAPT | |
| SCHEMBL27719772 | 0.82 | PDGFRB (0.56) | CYP1A2TDP1ATMMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807631-B1 | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO CO (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-5981752-A | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO COMPANY, LIMITED (JP) | 1999-11-09 | — | — | US | disclosed |
| US-5773618-A | PYRROLOQUINOLINONE DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0807631-A1 | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-11-19 | — | — | EP | disclosed |