SCHEMBL69736

SCHEMBL69736

COC(=O)[C@@H]1CC[C@H](C(=O)OC)O1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 1/20 0.47
PTPN1 P18031 1/20 0.47
PPP1CC P36873 1/20 0.47
PDK1 Q15118 1/20 0.37
TP53 P04637 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
MIF P14174 2/20 0.36
CHRNB2 P17787 2/20 0.35
CHRNA4 P43681 2/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA7 P36544 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
CYP1A2 P05177 1/20 0.34
HIF1A Q16665 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM3 P20309 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16570723 1.00 PPM1B (0.47) PPM1BPTPN1PPP1CCPDK1TP53
SCHEMBL21987133 0.91 PPM1B (0.50) PPM1BPTPN1PPP1CCPDK1TP53
SCHEMBL8013452 0.91 PPM1B (0.50) PPM1BPTPN1PPP1CCPDK1TP53
SCHEMBL71007 0.90 PPM1B (0.44) PPM1BPTPN1PPP1CCPDK1TP53
SCHEMBL19088423 0.86 PPM1B (0.41) PPM1BPTPN1PPP1CCPDK1TP53
SCHEMBL27449810 0.84 PPM1B (0.40) PPM1BPTPN1PPP1CCPDK1TP53
SCHEMBL10291155 0.84 PPM1B (0.40) PPM1BPTPN1PPP1CCPDK1TP53
SCHEMBL26741509 0.84 PPM1B (0.37) PPM1BPTPN1PPP1CCPDK1ALDH1A1
SCHEMBL22050970 0.84 PPM1B (0.37) PPM1BPTPN1PPP1CCPDK1ALDH1A1
SCHEMBL30354329 0.84 PPM1B (0.37) PPM1BPTPN1PPP1CCPDK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 PPM1B 3974/4885PTPN1 3997/4885PPP1CC 4613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.