SCHEMBL6974258

SCHEMBL6974258

CC(C1CCN(C(=O)OC(C)(C)C)CC1)C1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.55
RECQL P46063 1/20 0.53
EPHX1 P07099 1/20 0.53
USP2 O75604 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
MAPT P10636 2/20 0.51
NPC1 O15118 1/20 0.51
ALDH1A1 P00352 1/20 0.51
MAPK1 P28482 1/20 0.51
HTT P42858 1/20 0.51
RAB9A P51151 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
GPR119 Q8TDV5 7/20 0.50
DPP4 P27487 2/20 0.50
KDM4E B2RXH2 1/20 0.48
THRB P10828 1/20 0.48
PTPN2 P17706 1/20 0.48
PTPN1 P18031 1/20 0.48
PTPN6 P29350 1/20 0.48
EED O75530 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34461261 0.91 HPGD (0.48) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL4546601 0.89 HPGD (0.55) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL387237 0.88 HPGD (0.54) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL470530 0.88 HPGD (0.54) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL4523020 0.88 HPGD (0.54) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL5341723 0.88 HPGD (0.54) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL1714890 0.86 HPGD (0.53) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL3500032 0.86 DPP4 (0.54) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL2258037 0.86 DPP4 (0.54) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL8495308 0.86 HPGD (0.53) HPGDRECQLEPHX1USP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1098878-B1 BISPIPERIDINES AS ANTITHROMBOTIC AGENTS CEPHALON FRANCE (FR) 2003-12-17 EP disclosed
EP-1098878-A1 BISPIPERIDINES AS ANTITHROMBOTIC AGENTS LABORATOIRE L. LAFON (FR) 2001-05-16 EP disclosed
WO-2000003986-A1 BISPIPERIDINES AS ANTITHROMBOTIC AGENTS LABORATOIRE L. LAFON (FR) 2000-01-27 WO disclosed