Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 15/20 | 0.63 |
| ▸ | FNTB | P49356 | 15/20 | 0.63 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980402 | 1.00 | FNTA (0.63) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6979046 | 0.91 | FNTA (0.75) | FNTAFNTBPGGT1BCYP3A4GPBAR1 | |
| SCHEMBL7648937 | 0.91 | FNTA (0.75) | FNTAFNTBPGGT1BCYP3A4GPBAR1 | |
| SCHEMBL7644612 | 0.89 | FNTA (0.62) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL7087371 | 0.87 | FNTA (0.62) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL7649162 | 0.86 | FNTA (0.61) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL7644007 | 0.86 | FNTA (0.61) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL7645106 | 0.86 | FNTA (0.65) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL7643959 | 0.86 | FNTA (0.60) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6603201 | 0.83 | FNTA (0.71) | FNTAFNTBPGGT1BCYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045846-B1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2003-05-02 | — | — | EP | claimed |
| US-6472526-B1 | SHOWS AN INHIBITORY ACTIVITY AGAINST FARNESYL TRANSFERASE OR PHARMACEUTICALLY ACCEPTABLE SALTS OR ISOMERS THEREOF, IN PHARMACEUTICAL COMPOSITION AND INTERMEDIATES | LG CHEMICAL LTD. (KR) | 2002-10-29 | — | — | US | disclosed |