Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6969452 | 0.91 | F2 (0.48) | F2ALDH1A1PKMMEN1KMT2A | |
| SCHEMBL6983757 | 0.89 | F2 (0.63) | F2ALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL6986105 | 0.88 | F2 (0.62) | F2ALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL6969834 | 0.88 | F2 (0.54) | F2ALDH1A1PKMMEN1RECQL | |
| SCHEMBL6978094 | 0.88 | F2 (0.54) | F2ALDH1A1PKMMEN1RECQL | |
| Fumaric Acid SCHEMBL6961054 | 0.87 | F2 (0.54) | F2ALDH1A1PKMMEN1RECQL | |
| SCHEMBL6973921 | 0.87 | F2 (0.52) | F2 | |
| Hydrochloric Acid SCHEMBL7678913 | 0.87 | F2 (0.53) | F2ALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL7676997 | 0.86 | F2 (0.51) | F2ALDH1A1PKMRORC | |
| Hydrochloric Acid SCHEMBL6969224 | 0.86 | F2 (0.52) | F2ALDH1A1PKMMEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1220845-B1 | ARYL-SULFONAMIDE SUBSTITUTED BENZIMIDAZOL DERIVATIVES AND USE OF SAID AS TRYPTASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-08-13 | — | — | EP | disclosed |
| EP-1220845-A1 | ARYL-SULFONAMIDE SUBSTITUTED BENZIMIDAZOL DERIVATIVES AND USE OF SAID AS TRYPTASE INHIBITORS | Boehringer Ingelheim Pharma KG (DE) | 2002-07-10 | — | — | EP | disclosed |
| US-6413990-B1 | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-07-02 | — | — | US | disclosed |
| WO-2001023359-A1 | ARYL-SULFONAMIDE SUBSTITUTED BENZIMIDAZOL DERIVATIVES AND USE OF SAID AS TRYPTASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-04-05 | — | — | WO | disclosed |