SCHEMBL697519

SCHEMBL697519

COC(=O)OC1CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1078014 1.00 EPHX1 (0.39)
SCHEMBL10025768 0.93 EPHX2 (0.39)
SCHEMBL5676279 0.91 CYP1A2 (0.35)
SCHEMBL14609552 0.91 CYP19A1 (0.41)
SCHEMBL13321805 0.91 CYP19A1 (0.41)
SCHEMBL7554418 0.91 CYP1A2 (0.35)
SCHEMBL1081048 0.91 EPHX1 (0.52)
SCHEMBL10344338 0.90 EPHX1 (0.45)
SCHEMBL698655 0.90
SCHEMBL305953 0.90 EPHX1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250197410-A1 COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS GILEAD SCIENCES, INC. 2025-06-19 US disclosed
US-20240132513-A1 BENZAZEPINE DERIVATIVES, COMPOSITIONS, AND METHODS FOR TREATING COGNITIVE IMPAIRMENT AGENEBIO, INC. 2024-04-25 US disclosed
WO-2024039886-A1 BENZAZEPINE DERIVATIVES, COMPOSITIONS, AND METHODS FOR TREATING COGNITIVE IMPAIRMENT AGENEBIO, INC. (US) 2024-02-22 WO disclosed
US-9006225-B2 Stable pharmaceutical composition ASAHI KASEI PHARMA CORPORATION (JP) 2015-04-14 US disclosed
EP-2423199-A1 Substituted imidazoles and their use as pesticides Pfizer Limited (GB) 2012-02-29 EP disclosed
EP-2320732-A2 SUBSTITUTED IMIDAZOLE COMBINATIONS Pfizer Inc. (US) 2011-05-18 EP disclosed
US-7825149-B2 Substituted imidazoles PFIZER LIMITED (GB) 2010-11-02 US disclosed
EP-2236135-A1 STABLE PHARMACEUTICAL COMPOSITION Asahi Kasei Pharma Corporation (JP) 2010-10-06 EP disclosed
US-20100048893-A1 Substituted arylalkanoic acid derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2010-02-25 US disclosed
WO-2010020896-A2 SUBSTITUTED IMIDAZOLE COMBINATIONS PFIZER INC. (US) 2010-02-25 WO disclosed
US-6867320-B2 Substituted phenylalkanoic acid derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2005-03-15 US disclosed
WO-2005016862-A1 SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF ASAHI KASEI PHARMA CORPORATION (JP) 2005-02-24 WO disclosed
EP-1477472-A1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF Asahi Kasei Pharma Corporation (JP) 2004-11-17 EP disclosed
US-20040044258-A1 Substituted phenylalkanoic acid derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2004-03-04 US disclosed
US-5922888-A Process for removal of diol as impurity in cyclic carbonic acid ester MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1999-07-13 US disclosed
EP-0735034-B1 Process for removal of diol as impurity in cyclic carbonic acid ester MITSUI CHEMICALS INC (JP) 1999-07-07 EP disclosed
US-5827863-A Pyrazole derivatives as angiotensin II antagonists J. URIACH & CIA, S.A. (ES) 1998-10-27 US disclosed
EP-0735034-A1 Process for removal of diol as impurity in cyclic carbonic acid ester MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-10-02 EP disclosed
US-5475114-A Angiotensin-11 antagonist; therapeutical agent used for treating hypertension and chronic heart failure YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1995-12-12 US disclosed
EP-0646584-A1 PYRAZOLOTRIAZOLE DERIVATIVE YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1995-04-05 EP disclosed