Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL279619 | 0.82 | DAO (0.59) | DAOKMT2APOLBTDP1ALDH1A1 | |
| SCHEMBL15979700 | 0.81 | DAO (0.61) | DAOKMT2APOLBTDP1ALDH1A1 | |
| SCHEMBL6781684 | 0.81 | DAO (0.52) | DAOKMT2APOLBTDP1ALDH1A1 | |
| SCHEMBL280123 | 0.79 | DAO (0.55) | DAOKMT2APOLBTDP1ALDH1A1 | |
| SCHEMBL4140001 | 0.79 | DAO (0.59) | DAOKMT2APOLBTDP1ALDH1A1 | |
| SCHEMBL9372669 | 0.79 | DAO (0.59) | DAOKMT2APOLBTDP1ALDH1A1 | |
| SCHEMBL14157094 | 0.78 | POLB (0.50) | DAOKMT2APOLBTDP1ALDH1A1 | |
| SCHEMBL5551328 | 0.78 | DAO (0.48) | DAOKMT2APOLBTDP1ALDH1A1 | |
| SCHEMBL22721115 | 0.78 | DAO (0.57) | DAOKMT2APOLBTDP1ALDH1A1 | |
| SCHEMBL6394534 | 0.78 | GSK3B (0.62) | DAOKMT2APOLBTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240162-B1 | NOVEL DERIVATIVES OF 3-IMINO-1,2-DITHIOLES, METHOD FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SERVIER LAB (FR) | 2003-05-14 | — | — | EP | disclosed |
| EP-1240162-A2 | NOVEL DERIVATIVES OF 3-IMINO-1,2-DITHIOLES, METHOD FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Les Laboratoires Servier (FR) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001046180-A2 | NOVEL DERIVATIVES OF 3-IMINO-1,2-DITHIOLES, METHOD FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | LES LABORATOIRES SERVIER (FR) | 2001-06-28 | — | — | WO | disclosed |