Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1594522 | 0.98 | EPHX1 (0.43) | EPHX1CA12CA1CA2MMP2 | |
| SCHEMBL971123 | 0.98 | EPHX1 (0.43) | EPHX1CA12CA1CA2MMP2 | |
| SCHEMBL27923565 | 0.95 | — | — | |
| SCHEMBL745881 | 0.90 | — | — | |
| SCHEMBL27713854 | 0.79 | EPHX1 (0.42) | EPHX1CA12CA1CA2MMP2 | |
| SCHEMBL7494708 | 0.78 | CPN1 (0.47) | ATMSMN1; SMN2TSHR | |
| SCHEMBL17628753 | 0.77 | ACE (0.43) | EPHX1CA12CA1CA2MMP2 | |
| SCHEMBL417582 | 0.77 | ACE (0.43) | EPHX1CA12CA1CA2MMP2 | |
| SCHEMBL1572997 | 0.77 | EPHX1 (0.41) | EPHX1CA12CA1CA2MMP2 | |
| SCHEMBL9307 | 0.77 | ACE (0.43) | EPHX1CA12CA1CA2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957156-A | Compound containing benzoxazine structure, resin composition, prepreg and electric copper clad laminate, and preparation method and application thereof | 成都科宜高分子科技有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-115785124-B | KRAS G12D inhibitors and uses thereof | 润佳（苏州）医药科技有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-117986232-A | Oxime ester photoinitiator, preparation method and application thereof | 常州强力电子新材料股份有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-116284055-A | KRAS inhibitor and application thereof | 润佳（苏州）医药科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-115785124-A | KRAS G12D inhibitors and uses thereof | 润佳（苏州）医药科技有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-114957156-A | Compound containing benzoxazine structure, resin composition, prepreg and electric copper clad laminate, and preparation method and application thereof | 成都科宜高分子科技有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-111320714-B | Oxime ester photoinitiator, preparation method and application thereof | 常州强力先端电子材料有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-111320714-A | Oxime ester photoinitiator, preparation method and application thereof | 常州强力先端电子材料有限公司 | 2020-06-23 | — | — | CN | disclosed |
| CN-109629026-A | A kind of cellulose melt spun fibre and preparation method thereof with durable antibiotic performance | 东华大学 | 2019-04-16 | — | — | CN | disclosed |
| CN-108329828-A | Resistance to ag(e)ing, water resistance, oil resistivity Water-based ceramic-imitating coating and preparation method thereof | 段宝荣 | 2018-07-27 | — | — | CN | disclosed |
| US-4661512-A | Adamantanamine derivatives, processes for their preparation and drugs in which they are present | S. A. PANMEDICA (FR) | 1987-04-28 | — | — | US | disclosed |
| US-4242334-A | ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-12-30 | — | — | US | disclosed |
| US-4178381-A | C-homoestratrienes | SCHERING, AKTIENGESELLSCHAFT (DE) | 1979-12-11 | — | — | US | disclosed |
| US-4124707-A | 7α-Halogeno-3,20-dioxo-1,4-pregnadienes, methods for their manufacture, their use as anti-inflammatory agents, and pharmaceutical formulations useful therefor | SCHERING CORPORATION (US) | 1978-11-07 | — | — | US | disclosed |
| US-4097496-A | ANTIPROSTAGLANDIN ACTIVITY | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-06-27 | — | — | US | disclosed |
| US-4076708-A | Process for the preparation of 7α-halogeno-3-oxo-4-dehydro steroids and novel 7α-halogeno derivatives produced thereby | SCHERING CORPORATION (US) | 1978-02-28 | — | — | US | disclosed |
| US-4038299-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | SYNTEX (U.S.A.) INC. (US) | 1977-07-26 | — | — | US | disclosed |
| US-3984459-A | ANTI-PROSTAGLANDINS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-10-05 | — | — | US | disclosed |
| US-3966820-A | ANALGESICS, ANTIINFLAMMATORY, ANTIPYRETICS | SYNTEX (U.S.A.) INC. (US) | 1976-06-29 | — | — | US | disclosed |
| US-3950408-A | Process for preparing [1-oxo-2-cyclopentyl (or 2-isopropyl)-2-methyl-6,7-dichloro-5-indanyloxy] acetic acid | MERCK & CO., INC. (US) | 1976-04-13 | — | — | US | disclosed |