Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 16/20 | 0.70 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3089442 | 0.84 | HDAC6 (0.68) | HDAC6HDAC1HDAC4HDAC3HPGDS | |
| SCHEMBL3089445 | 0.84 | HDAC6 (0.68) | HDAC6HDAC1HDAC4HDAC3HPGDS | |
| SCHEMBL3094688 | 0.83 | HDAC6 (1.00) | HDAC6HDAC1HDAC4HDAC3HPGDS | |
| SCHEMBL13838820 | 0.82 | CYP3A4 (0.54) | HDAC6HDAC1HPGDSHSD17B1HSD17B2 | |
| SCHEMBL2224563 | 0.78 | HDAC6 (1.00) | HDAC6HDAC1HDAC4HDAC3HPGDS | |
| SCHEMBL3098643 | 0.76 | HDAC6 (1.00) | HDAC6HDAC1HDAC4HSD17B1HSD17B2 | |
| SCHEMBL1891576 | 0.76 | ERN1 (0.57) | HDAC6HDAC1HDAC4HDAC3HPGDS | |
| SCHEMBL3097716 | 0.75 | HDAC6 (0.71) | HDAC6HDAC1HDAC4HDAC3HSD17B1 | |
| SCHEMBL18003262 | 0.75 | PRF1 (0.47) | HDAC6HDAC1HDAC4HSD17B1HSD17B2 | |
| SCHEMBL4655054 | 0.74 | HDAC6 (0.71) | HDAC6HDAC1HDAC4HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088181-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2011-07-21 | — | — | WO | disclosed |