SCHEMBL6976450

SCHEMBL6976450

CC[CH]NC(C)(C)C1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 2/20 0.38
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
EPHX1 P07099 1/20 0.32
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6976456 0.98 SSTR4 (0.35) SSTR4MEN1ALDH1A1LMNAALOX12
SCHEMBL6975447 0.89
SCHEMBL6969397 0.84 CYP1A2 (0.33) SSTR4CYP1A2
SCHEMBL6965754 0.82 CYP1A2 (0.30) SSTR4CYP1A2
SCHEMBL6977121 0.76 SSTR4 (0.37) SSTR4EPHX1
SCHEMBL6977814 0.73 SSTR4 (0.34) SSTR4
SCHEMBL6975579 0.72
SCHEMBL4872250 0.70 SSTR4 (0.43) SSTR4MEN1ALDH1A1LMNAALOX12
SCHEMBL24761927 0.69 SSTR4 (0.41) SSTR4MEN1ALDH1A1LMNAALOX12
SCHEMBL13682899 0.69 SSTR4 (0.41) SSTR4MEN1ALDH1A1LMNAALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0870765-B1 AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS ZERIA PHARM CO LTD (JP) 2003-11-19 EP disclosed
US-5981557-A HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT ZERIA PHARMACEUTICAL CO., LTD. (JP) 1999-11-09 US disclosed
EP-0870765-A1 AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS ZERIA PHARMACEUTICAL CO., LTD. (JP) 1998-10-14 EP disclosed