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(Ethenylsulfonyl)Benzene

(Ethenylsulfonyl)Benzene

SCHEMBL6976730

C=CS(=O)(=O)c1ccccc1.N=C1CCCCC(CCS(=O)(=O)c2ccccc2)N1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 1/20 0.52
▸ RAB9A P51151 2/20 0.36
▸ POLB P06746 1/20 0.36
▸ HTR7 P34969 1/20 0.35
▸ MAPT P10636 2/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ GAA P10253 1/20 0.35
▸ NPC1 O15118 1/20 0.32
▸ CRBN Q96SW2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6975751 0.91 KMT2A (0.61) KMT2ARAB9APOLBHTR7MAPT
SCHEMBL6973440 0.73 MAPK1 (0.47) KMT2ARAB9AHTR7ALDH1A1
SCHEMBL6968385 0.69 POLB (0.41) POLB
SCHEMBL6975587 0.68 SLC18A3 (0.39) POLB
Hydrochloric Acid SCHEMBL6980655 0.68 SLC18A3 (0.39) —
SCHEMBL6969024 0.68 HPGD (0.40) POLBALDH1A1
SCHEMBL6971463 0.65 POLB (0.56) POLBCRBN
(Ethenylsulfonyl)Benzene SCHEMBL45672 0.65 TLR9 (0.58) RAB9AMAPTALDH1A1NPC1
(Ethenylsulfonyl)Benzene SCHEMBL1332952 0.65 TLR9 (0.58) RAB9AMAPTALDH1A1NPC1
(Ethenylsulfonyl)Benzene SCHEMBL1331367 0.65 TLR9 (0.58) RAB9AMAPTALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0821674-B1 CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS SEARLE & CO (US) 2003-08-06 — — EP claimed