Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5535693 | 0.92 | MAOB (0.46) | MAOBRAB9ANPC1MAOACYP1A2 | |
| SCHEMBL15079869 | 0.86 | MAOB (0.58) | MAOBRAB9ANPC1MAOACYP1A2 | |
| SCHEMBL5540879 | 0.85 | MAOB (0.44) | MAOBMAOAAPPDRD2DRD4 | |
| SCHEMBL28376353 | 0.83 | KCNH2 (0.46) | MAOBRAB9ANPC1APP | |
| SCHEMBL5958007 | 0.82 | NPC1 (0.56) | MAOBRAB9ANPC1MAOADRD2 | |
| SCHEMBL15079872 | 0.80 | NPC1 (0.69) | MAOBRAB9ANPC1MAOACYP1A2 | |
| SCHEMBL15456066 | 0.79 | TAAR1 (0.52) | MAOBL3MBTL1 | |
| SCHEMBL6507424 | 0.79 | NPC1 (0.45) | MAOBRAB9ANPC1MAOACYP1A2 | |
| SCHEMBL832700 | 0.78 | NPC1 (0.61) | MAOBRAB9ANPC1MAOADRD2 | |
| SCHEMBL833408 | 0.78 | KCNH2 (0.49) | MAOBAPPFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108929281-A | Triazole compound and synthesis method and application thereof | 华东师范大学 | 2018-12-04 | — | — | CN | disclosed |
| EP-1343756-A2 | 1-ARYL- OR 1-ALKYLSULFONYL-HETEROCYCLYLBENZAZOLES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | Wyeth (US) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002036562-A2 | 1-ARYL- OR 1-ALKYLSULFONYL-HETEROCYCLYLBENZAZOLES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2002-05-10 | — | — | WO | disclosed |