Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5107874 | 0.95 | CHRNB4 (0.44) | CHRNB4CHRNA3CHRNA7KCNH2HTR3A | |
| SCHEMBL5108247 | 0.92 | CHRNB4 (0.49) | CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL5116146 | 0.92 | CHRNB4 (0.46) | CHRNB4CHRNA3CHRNA7KCNH2 | |
| Hydrochloric Acid SCHEMBL5121891 | 0.91 | CHRNB4 (0.48) | CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL5123104 | 0.87 | CHRNB4 (0.52) | CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL5110318 | 0.84 | CHRNB4 (0.47) | CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL5111991 | 0.84 | CHRNA7 (0.41) | CHRNB4CHRNA3CHRNA7KCNH2HTR3A | |
| SCHEMBL5114127 | 0.83 | CHRNB4 (0.44) | CHRNB4CHRNA3CHRNA7KCNH2HTR3A | |
| SCHEMBL5107938 | 0.83 | CHRNB4 (0.47) | CHRNB4CHRNA3CHRNA7KCNH2HTR3A | |
| SCHEMBL5108171 | 0.82 | CHRNB4 (0.42) | CHRNB4CHRNA3CHRNA7KCNH2HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135389-B1 | 1,4-DIAZABICYCLO 3.2.2]NONANE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATION | SANOFI SYNTHELABO (FR) | 2003-09-10 | — | — | EP | disclosed |
| US-6407095-B1 | TREATING NICOTINIC RECEPTOR, GASTROINTESTINAL, NERVOUS SYSTEM, PSYCHOLOGICAL, AND BRAIN DISORDERS | SANOFI-SYNTHELABO (FR) | 2002-06-18 | — | — | US | disclosed |