Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.57 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | CCR8 | P51685 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977079 | 1.00 | KCNH2 (0.57) | KCNH2SLC2A1CCR8 | |
| SCHEMBL6975581 | 0.95 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL6975577 | 0.95 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL7720427 | 0.92 | KCNH2 (0.59) | KCNH2SLC2A1 | |
| SCHEMBL7720435 | 0.92 | KCNH2 (0.59) | KCNH2SLC2A1 | |
| SCHEMBL7720429 | 0.92 | KCNH2 (0.59) | KCNH2SLC2A1 | |
| SCHEMBL7720767 | 0.91 | KCNH2 (0.58) | KCNH2SLC2A1 | |
| SCHEMBL7720772 | 0.91 | KCNH2 (0.58) | KCNH2SLC2A1 | |
| SCHEMBL6608754 | 0.90 | KCNH2 (0.70) | KCNH2 | |
| SCHEMBL6608743 | 0.90 | KCNH2 (0.70) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051413-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-06-04 | — | — | EP | claimed |