Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 7/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6979576 | 0.88 | GNRHR (0.60) | GNRHR | |
| SCHEMBL6982311 | 0.86 | GNRHR (0.61) | GNRHR | |
| SCHEMBL7905685 | 0.82 | KDM4E (0.48) | — | |
| SCHEMBL6975952 | 0.82 | GNRHR (0.76) | GNRHR | |
| SCHEMBL7543850 | 0.78 | GNRHR (0.50) | GNRHR | |
| SCHEMBL8698127 | 0.77 | GNRHR (0.63) | GNRHR | |
| SCHEMBL7899439 | 0.76 | GNRHR (0.55) | GNRHR | |
| SCHEMBL7912498 | 0.76 | GNRHR (0.48) | GNRHR | |
| SCHEMBL7905635 | 0.75 | GNRHR (0.64) | GNRHR | |
| SCHEMBL6974859 | 0.75 | GNRHR (0.61) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095038-B1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO INC (US) | 2003-09-03 | — | — | EP | disclosed |
| EP-0873336-B1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO INC (US) | 2002-03-27 | — | — | EP | disclosed |
| EP-1095038-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (US) | 2001-05-02 | — | — | EP | disclosed |
| US-6200957-B1 | USEFUL FOR TREATMENT OF VARIETY OF SEX-HORMONE RELATED AND OTHER CONDITIONS IN BOTH MEN AND WOMEN | MERCK & CO., INC. | 2001-03-13 | — | — | US | disclosed |
| WO-2000004013-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 2000-01-27 | — | — | WO | disclosed |