Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 5/20 | 0.58 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977675 | 1.00 | ITGB1 (0.58) | ITGB1ITGA4HTTMEN1KMT2A | |
| SCHEMBL6963937 | 0.89 | ITGB1 (0.60) | ITGB1ITGA4HTTMEN1KMT2A | |
| SCHEMBL6963934 | 0.89 | ITGB1 (0.60) | ITGB1ITGA4HTTMEN1KMT2A | |
| SCHEMBL6972201 | 0.82 | ITGB1 (0.66) | ITGB1ITGA4HTTMEN1KMT2A | |
| SCHEMBL6972192 | 0.82 | ITGB1 (0.66) | ITGB1ITGA4HTTMEN1KMT2A | |
| SCHEMBL6977320 | 0.81 | ITGB1 (0.67) | ITGB1ITGA4HTTMEN1KMT2A | |
| SCHEMBL6977318 | 0.81 | ITGB1 (0.67) | ITGB1ITGA4HTTMEN1KMT2A | |
| SCHEMBL6512426 | 0.74 | ITGB1 (0.53) | ITGB1ITGA4HTTMEN1KMT2A | |
| SCHEMBL6512435 | 0.72 | ITGB1 (0.57) | ITGB1ITGA4HTTMEN1KMT2A | |
| SCHEMBL6514009 | 0.70 | ITGB1 (0.58) | ITGB1ITGA4HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095036-B1 | CINNAMIC ACID DERIVATIVES AS CELL ADHESION MOLECULES | CELLTECH THERAPEUTICS LTD (GB) | 2003-05-07 | — | — | EP | disclosed |
| US-6465471-B1 | INHIBIT BINDING OF ALPHA 4 INTEGRINS TO THEIR LIGANDS THUS THEY ARE OF USE IN PROPHYLAXIS AND TREATMENT OF IMMUNE OR INFLAMMATORY DISORDERS | CELLTECH THERAPEUTICS LIMITED (GB) | 2002-10-15 | — | — | US | disclosed |